Do not open nozzle fully when bottle is under pressure. Before using pesticides, use water to set optimal nozzle spray setting. Wash bottle thoroughly before and after use. Do not mix different pesticides/chemicals together. Do not leave unused chemicals in ther bottle. When using pesticides/chemicals do not over pump, rather use smaller and more frequent intervals when pumping. Always wear protective clothing. Ensure that the vessel and pump mechanism have not been damaged proir to use.